asthma control in children
Conditions
Interventions
This will be a cross-sectional study. Data will be collected once per patient in a period of 6 months, in the same occasion as their routine visit in the outpatient clinics. Asthma control will be eva
Sponsors
Academic Medical Centre
University of Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males and females aged 6 to 17 years (inclusive); 2. Parent/ guardian must be able to give written informed consent prior to participation in the study, which includes ability to comply with the requirements and restrictions listed in the consent form. Informed consent must be obtained prior to undertaking any study procedures; 3. Assent should be obtained from all children in the study where appropriate; 4. For children in the asthma groups, the diagnosis of asthma should be given by specialists according to the GINA guidelines; 5. For the control-group children should have no known respiratory or other systemic diseases.
Exclusion criteria
Exclusion criteria: 1. Known underlying respiratory tract disease like congenital airway abnormalities, cystic fibrosis, primary ciliary dyskinesia, bronchopulmonary dysplasia or bronchiectasis; 2. Known systemic or inflammatory diseases; 3. History or current evidence of an upper or lower respiratory infection or symptoms (including common cold) within 2 weeks of baseline assessment (assessment should be deferred); 4. The child has had a exacerbation (requiring ER attendance or hospital admission and /or a course of high dose OCS for at least 3 days duration) within 4 weeks of the baseline assessment (assessment should be deferred).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Asthma control score; 2. VOC’s of breath prints in exhaled air by gas chromatography mass spectrometry (GC-MS) and electronic nose (eNose). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Fractional exhaled Nitric Oxide; 2. FEV1, PEF. | — |
Contacts
Public ContactPeter J. Sterk
Dept. Pulmonology, F5-259 Academic Medical Center University of Amsterdam P.O. Box 22700
Outcome results
None listed