Subfertility
Conditions
Interventions
Patients are inseminated approximately 3-4 hours after the production of semen (Group I, current practice VUmc) or patients are inseminated as soon as possible after the production of semen (Group II,
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Patients who start their first IUI treatment. All subsequent cycles fall within this study. Only patients who undergo six IUI cycles, three times in a natural cycle and three times in a stimulated cycle, fall within this study. Patients who start a new IUI treatment after an ongoing pregnancy. Both IUI performed in a natural cycle and stimulated cycles fall within this study. Patients with well-adjusted, non-endocrine hormonal pathology fall within this study.
Exclusion criteria
Exclusion criteria: Patients who have IUI with donorsemen. Patients in which the semen was obtained in a different way than masturbation (bladder irrigation, electrical stimulation). Patients who have less than 0.5 million progressive motile sperm left over after work-up of semen. Patients with polycystic ovarian syndrome (PCOS). Patients with imminent ovarian failure (basal FSH> 10 IU / l).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate per patient couple (positive fetal cardiac activity 10 weeks after IUI). | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate per IUI cycle (HCG> 50 IU /l at 16 days after IUI). Ongoing pregnancy rate per IUI cycle (positive fetal cardiac activity 10 weeks after IUI). Percentage multiple pregnancies Percentage biochemical pregnancies and abortions Percentage/number of live births. | — |
Contacts
Public ContactC.G. Vergouw
VU University medical center PO box 7057
Outcome results
None listed