Breast cancer Borstkanker Mamma carcinoom
Conditions
Interventions
CT scan before each fraction of partial breast irradiation using the Cyberknife stereotactic radiotherapy system
Sponsors
Erasmus MC, Rotterdam, The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: - Female - Age > or = 50 years - Stage pTis, pT1 or pT2 (tumor size or = 2mm for DCIS - ER positive - pN0 confirmed by sentinel node biopsy or axillary lymph node dissection - At least 3 surgical clips in the tumor bed, being large titanium or tantalum type
Exclusion criteria
Exclusion criteria: - Lympho-vascular infiltration - Extensive intraductal component - Multifocal or multicentric disease - Invasive lobular carcinoma - Distant metastasis - Neoadjuvant chemotherapy - Prior irradiation to the chest - Inability to read Dutch
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| geometric uncertainty of Cyberknife APBI and required PTV margin | — |
Secondary
| Measure | Time frame |
|---|---|
| - Proportion of patients where the surgical clips and superficial gold markers can successfully be used as fiducials - Dosimetric gain of PTV margin reduction - Acute toxicity | — |
Contacts
Public ContactN. Hoekstra
Postbus 5201
Outcome results
None listed