Use of NIRS during mechanical thrombectomy for ischaemic stroke

Use of near infrared spectroscopy during mechanical thrombectomy for ischaemic stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON25450

Enrollment

Registered

2018-10-10

Start date

2018-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic stroke, Intra-arterial thrombectomy, Near infrared spectroscopy Ischemische beroerte, intra-arteriële trombectomie, bijna infrarode spectroscopie

Interventions

Before the IAT, a NIRS sensor will be applied to the skull, bilaterally, directly above the flow region of the middle cerebral artery (MCA). ADDENDUM (06-07-2019): On arrival in the angiography suit

Eligibility

Inclusion criteria

Inclusion criteria: - Equal or above 18 years of age - An ischemic stroke caused by a proximal arterial occlusion of the MCA - Eligible to undergo IAT under general anaesthesia

Exclusion criteria

Exclusion criteria: - Consent is not given by patient or his/her legal representative.

Design outcomes

Primary

Measure	Time frame
1. Periprocedural cerebral oxygenation of the ischemic and non-ischemic hemisphere; specifically: - Before and after the induction of anaesthesia - Before and after the thrombectomy (reperfusion) - Before and after the end of anaesthesia 2. Neurological outcome quantified by: - NIHHS score	—

Secondary

Measure	Time frame
1. Demographic parameters 2. Radiological imaging: - Location of the vascular occlusion and the level of collateral vasculature - Modified Thrombolysis In Cerebral Infarction (mTICI)-score after thrombectomy - Physiological and pharmacological variables before, during and after the procedure - Physiological variables: Heart rate, invasive blood pressure, non-invasive blood pressure, FiO2, CO2, arterial haemoglobin saturation, EEG measure (if used) - Pharmacological variables: drugs used, doses and concentrations administered	—

Measure

Time frame

1. Demographic parameters 2. Radiological imaging: - Location of the vascular occlusion and the level of collateral vasculature - Modified Thrombolysis In Cerebral Infarction (mTICI)-score after thrombectomy - Physiological and pharmacological variables before, during and after the procedure - Physiological variables: Heart rate, invasive blood pressure, non-invasive blood pressure, FiO2, CO2, arterial haemoglobin saturation, EEG measure (if used) - Pharmacological variables: drugs used, doses and concentrations administered

—

Contacts

Public ContactR. Spanjersberg

Hanzeplein 1

r.spanjersberg@umcg.nl+31 (0)50 3611158

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)