Critical congenital heart defects Potential threatening pathology causing hypoxemia in the neonate, such as persistent pulmonary hypertension, infection or sepsis.
Conditions
Interventions
Pulse oximetry reading at least one hour after birth at right hand and either foot.
Pulse oximetry reading at day two or three at right hand and either foot.
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Infants born in the Amsterdam-Leiden region.
Exclusion criteria
Exclusion criteria: Infants where pre and post ductal pulse oximetry is performed for at least 24 hours for monitoring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of the screening for critical congenital heart defects: sensitivity, specificity, false positive rate, positive predictive value, negative predictive value. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cost-effectiviness of the screening; Detection of other possible life threatening pathology, such as persistent pulmonary hypertension of the newborn, infection, sepsis, non-critical congenital heart defects; Problems identified in the use of PO in home setting; Problems identified with referral logistics | — |
Contacts
Public ContactI. Narayen
Neonatologie, Postzone J6-S, Leiden University Medical Center
Outcome results
None listed