ANTARCTICA trial: Cryo-thawed embryo transfer: natural versus artificial cycle. A non inferiority trial.

Cryo-thawed embryo transfer: natural versus artificial cycle. A non inferiority trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25356

Enrollment

1150

Registered

2009-01-13

Start date

2009-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

EN: subfertility, cryo thawed embryo transfer, IVF NL: subfertiliteit, gecryopreserveerder embryo's, IVF

Interventions

Cryo thawed embryo transfer in natural cycle versus artificial cycle.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between 18 en 40, planning to receive a frozen thawed embryo transfer, embryos orginated out of IVF/ICSI treatment 1,2 or 3. 2. Patients are willing to participate during 1 frozen thawed embryo transfer treatment cycle and are willing to sign informed consent. 3. Ovulatoir menstruationcycle between 26 and 35 days.

Exclusion criteria

Exclusion criteria: Patients with a contraindication for medication used in this study such as: 1. Trombo-embolic event in the patients history; 2. Severe disorder of liverfunction; 3. Estrogen sensitive tumors; 4. Breastcancer; 5. Porfyria; 6. Patients with a known allergy for one of the used medicines; 7. Patients with anovulatory menstruation cycles; 8. Patients with uterine abnormalities; 9. Patients with cryo embryos derrived from oocyte donation.

Design outcomes

Primary

Measure	Time frame
Live birth rate.	—

Secondary

Measure	Time frame
1. Clinical pregnancy, ongoing pregnancy, cancellation rates (per started cryo cycle). 2. Endometrial growth. 3. Cost efficiancy and analyses of the burden of treatment. 4. SAE.	—

Contacts

Public ContactE.R. Groenewoud

Postbus 10400

e.r.groenewoud@isala.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)