Psoriasis of the vingernails.
Conditions
Interventions
On left and right vingernails either placebo, either 100mg/ml ciclosporin application, twice daily.
The duration of the treatment is till complete cure or for a maximum of 16 weeks.
Control group ma
Sponsors
Erasmus MC
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of psoriasis of fingernails in both hands; 2. In cases of oral treatment with methotrexate, prednisone or fumarates, the dose of medication before the start has to be constant for 8 weeks and it may be reasonably expected that the dose shall not be altered during the treatment phase of the study; 3. A minimum of at least 2 affected nails on the left hand and the right hand, and the number of affected nails may differ by 1 nail at the maximum on the left hand compared with those on the right hand.
Exclusion criteria
Exclusion criteria: 1. Systemic treatment with cyclosporine or a biological agent (efaluzimab, etanercept or related medication); 2. Change of oral medication 8 weeks before the start of the trial; 3. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NAPSI scores. | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevention? Does the NAPSI correlate with patientsatisfaction? | — |
Contacts
Public ContactAnnik Rengen, van
Erasmus Medical Center Rotterdam, Dr. Molewaterplein 40, P.O. Box 2040
Outcome results
None listed