Chlorhexidine-alcohol versus iodine-alcohol for surgical-site antisepsis

A PRAGMATIC MULTICENTER CLUSTER RANDOMISED CROSS-OVER TRIAL COMPARING CHLORHEXIDINEALCOHOL AND IODINE-ALCOHOL FOR SURGICAL-SITE ANTISEPSIS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON25242

Enrollment

4000

Registered

2013-05-21

Start date

2013-07-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical-site infection, postoperatieve wondinfectie, POWI, SSI

Interventions

Participating hospitals are randomly assigned to either chlorhexidine-alcohol (0.5% chlorhexidine in alcohol 70%) or iodine-alcohol (1% iodine in alcohol 70%) for preoperative skin antisepsis for a ti

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing general surgical and/or orthopedic indicator operations that are reported to Prezies-network.

Exclusion criteria

Exclusion criteria: - Inability to complete 30 days follow-up; - < 18 years of age; - Evidence of infection at or adjacent to the operative site; - History of allergy for chlorhexidine, alcohol or idiophors.

Design outcomes

Primary

Measure	Time frame
Primary endpoint is the occurrence of SSI within 30 days following surgery or within one year following orthopaedic procedures.	—

Secondary

Measure	Time frame
Secondary endpoints are variations in SSI between indicator operations, wound classification and wound type.	—

Contacts

Public ContactCharehbili

a.charehbili@lumc.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)