neuropathic post-cancer pain,
Conditions
Interventions
All patients will have a trial stimulation period with an external SCS pulse generator. If the trial is successful ( > 50% pain reduction) an SCS system will be implanted. After 1, 3 and 6 months of S
Sponsors
Medisch Spectrum Twente
Eligibility
Inclusion criteria
Inclusion criteria: 1. Peripheral neuropathic pain in lower extremities that exists for more than 6 months and is due to chemotherapy or radiotherapy; 2. Patient cannot be treated further otherwise according to patients’ medical specialist; 3. Physiotherapy and/or manual therapy, lumbar sympathetic ganglion and/or RIS-blocks and/or oral medication give insufficient pain relief or unacceptable side-effects; 4. The pain-sensation on a visual analogue scale is 5 or more (recording both for day and night time).
Exclusion criteria
Exclusion criteria: 1. Age < 18 years; 2. Psychological problems that requires treatment; 3. Addiction (i.e. compulsory) to: drugs, alcohol, medication; 4. Insufficient cooperation by patient (motivation, insight or communication); 5. Coagulation irregularities/ Anti-coagulants; 6. Immune compromised; 7. Life expectancy less than 1 year; 8. Pregnancy; 9. Local infection at the site of the incision; 10. Implanted pacemaker, ICD or other neuromodulation system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in neuropathic pain as measured by VAS score after 6 months of SCS. | — |
Secondary
| Measure | Time frame |
|---|---|
| An evaluation of the efficacy of SCS Treatment in patients with post cancer neuropathic pain as measured by change in pain intensity at all visits, and an evaluation of other health outcome measures. | — |
Contacts
Public ContactC.C. Vos, de
Medisch Spectrum Twente, Department of Neurosurgery, P.O. Box 50000
Outcome results
None listed