differentiation, colonoscopy, white light, WavSTAT, optical diagnosis
Conditions
Interventions
None listed
Sponsors
Academic Medical Centre, Amsterdam, the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age > 18 years; 2. Patients who are advised to undergo colonoscopic surveillance because of: A. A history of adenomatous polyps; B. Symptoms (e.g. change in bowel habits); C. Family history of CRC.
Exclusion criteria
Exclusion criteria: 1. Poor bowel preparation (scoring ≤ 4 points on the Boston Bowel Preparation Scale 8); 2. Polyposis syndromes; 3. History of inflammatory bowel disease; 4. Presence of conditions precluding histological sampling of the colon (e.g. coagulation disorders, anticoagulant therapy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The overall accuracy of the WavSTAT represented by the sensitivity and specificity using final histopathology as golden standard; 2. The accuracy of the WavSTAT of lesions that are differentiated with white light endoscopy with low confidence, represented by the sensitivity and specificity using final histopathology as golden standard. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The percentage of lesions that is differentiated with white light endoscopy with high confidence; 2. The difference between trainees and expert endoscopists regarding the percentage of lesions that is differentiated with high confidence with white light endoscopy; 3. The accuracy for predicting histopathology in lesions that are differentiated with high confidence with white light endoscopy; 4. The difference in accuracy between trainees and expert endoscopists for predicting histopathology in lesions that are differentiated with high confidence with white light endoscopy. | — |
Contacts
Public ContactEvelien Dekker
Academic Medical Center (AMC) Department of Gastroenterology and Hepatology P.O. Box 22660
Outcome results
None listed