Pancreatitis Acute pancreatitis Idiopathic pancreatitis Idiopathische pancreatitis Idiopathic acute pancreatitis Idiopathische acute pancreatitis Endoscopic ultrasonography Endoscopic ultrasound Endo-echo Endoscopische echografie Endoscopische echo Aetiology Etiology Etiologie
Conditions
Interventions
Endoscopic ultrasound
Sponsors
Prof. Dr. P. Fockens, MD, PhD
Head of department Department of Gastroenterology & Hepatology
C2-330
Academic Medical Center
Meibergdreef 9
1105 AZ, Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients older than 18 years 2. First episode of idiopathic acute pancreatitis 3. Informed consent for participation
Exclusion criteria
Exclusion criteria: 1. Patients in whom an aetiology is found in standard work-up 2. Diagnosis of chronic pancreatitis (according to the M-ANNHEIM classification) in standard work-up 3. Recurrent pancreatitis 4. Altered anatomy which prohibits the endoscopist from visualizing gall bladder, bile ducts, pancreas or pancreatic duct via endoscopic ultrasound (such as gastric bypass surgery) 5. Patients in which an endoscopic ultrasound is performed before inclusion, either during or after the index admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of patients with idiopathic acute pancreatitis in whom endoscopic ultrasound detects gallstone disease or other causes of pancreatitis (such as chronic pancreatitis or pancreatic tumours). Positive imaging is defined as imaging during which a definitive cause for the acute pancreatitis episode can be found; or during which abnormalities are visualized in which, after obtaining tissue and pathological examination, pathological tissue is found. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Recurrence rate of acute pancreatitis in “endoscopic ultrasound-negative” idiopathic acute pancreatitis 2. Severity of recurrent pancreatitis (according to the revised Atlanta classification) 3. Readmission 4. Additional invasive interventions: a. Cholecystectomy b. Endoscopic sphincterotomy 5. Complications of interventions, according to the Clavien-Dindo classification a. Endoscopic procedures: perforation, bleeding, cholangitis, post-procedure pancreatitis, infection (defined as fever and bacteraemia), sedation-related complications or other complications b. Cholecystectomy: perforation, bleeding, bile duct injury, infection (defined as fever and positive blood, wound or specimen culture), sedation-related complications or other complications 6. Length of hospital stay 7. Quality of life 8. Mortality 9. Costs | — |
Contacts
Public ContactDevica Umans
St. Antoniusziekenhuis; Pancreatitis Werkgroep Nederland; PO Box 2500; 2420 EM Nieuwegein
Outcome results
None listed