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The effect of L-arabinose on glycaemic and insulinemic response in a liquid and a solid product.

The effect of L-arabinose on glycaemic and insulinemic response in a liquid and a solid product.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON25121
Enrollment
18
Registered
2016-06-17
Start date
2016-05-24
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eating behaviour, overweight, obesity, nutritional disorders en metabolic diseases (incl. diabetes)

Interventions

1) Sugar drink
2) L-arabinose and Sugar drink
3) L-arabinose drink
4) Sugar clusters
5) L-arabinose clusters low dose
6) L-arabinose clusters high dose

Sponsors

Wageningen University (WUR)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • 18-35 Years old while signing the informed consent • Good Dutch speaking, writing, understanding • Healthy: as judged by the subject • Stable body weight, i.e. no reported weight loss or weight gain of > 5 kg in the two months prior to the screening session • Normal fasting glucose concentration 8.5 mmol/L for men and >7.5 mmol/L for females, measured by finger prick

Exclusion criteria

Exclusion criteria: • Women being pregnant or lactating • Allergy, intolerance or oversensitivity for food products • Having reported gastro-intestinal problems • Having a history of medical or surgical events that may affect the study outcome • Medical drug use (except for contraceptives) that may affect the study outcome • Current antibiotics usage or in the two months prior to the screening session • Not willing to eat or drink the test products • Use of dietary supplements that may affect the study outcome • Currently using a slimming or medically prescribed diet or having used one in the two months prior to the screening session • Excessive alcohol consumption (>21 glasses/week on average) • Planning to change physical activity pattern during the study period • Having blood vessels that are too difficult for inserting a cannula, as judged by the study nurse • Recent blood donation (<1 month prior to Day 1 of the study) • Planning to donate blood as a blood donor during the study • Not having a general practitioner • Being an employee or student doing a thesis or internship of Wageningen University, department of Human Nutrition • Current participation in other research

Design outcomes

Primary

MeasureTime frame
blood glucose and insulin levels

Secondary

MeasureTime frame
appetite feelings, GLP-1 levels, ad libitum food intake, acceptability of the products, L-arabinose levels, excretion of L-arabinose

Contacts

Public ContactKorrie Pol

Wageningen UR, Afdeling Humane Voeding, Bode 62

korrie.pol@wur.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)