Surgical site infections (SSI's), randomised study, randomized controlled trial,
Conditions
Interventions
The EPOCH bundle
An evidence-based, enhanced perioperative care program that can be applied without introduction of new material in the OR, added on top of usual care, comprising of: 1. Normothermia,
Sponsors
Academic Medical Center (AMC), Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: - Adult patients ¡Ý 18 years - Elective open abdominal surgery and laparoscopic colorectal surgery
Exclusion criteria
Exclusion criteria: - Emergency surgery - Reoperation for complications from recent surgery (within 3 months) - The inability of reading/understanding and filling in the questionnaires - Participation in another study with interference of study outcomes - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of SSI evaluated from the Dutch National Surgical Complication Registry (LHCR). Parallel assessment of incidence rate of SSI by the CDC definition through medical chart reviews. | — |
Secondary
| Measure | Time frame |
|---|---|
| - SSI rate evaluated at 30 days and 3 months follow-up by the CDC definition through medical chart review. - Readmission rate at 30 days follow up through LHCR registration - WHO disability assessment schedule 2.0 by self-administration through online/paper-form questionnaires at postop day 30, 60 and 90. - (In)direct medical and non-medical costs, quality adjusted life years (QALY) (Methods described under CEA and BIA. See below) - Anastomotic leakage rate at 30 days follow up through LHCR registration and medical chart review. - Incisional hernia rate by medical chart review (diagnosed by either physical examination and/or ultrasonography or CT) one year after surgery. | — |
Contacts
Public ContactNiels Wolfhagen
Academisch Medisch Centrum - Afdeling chirurgie G4-134
Outcome results
None listed