Barrett's esophagus
Conditions
Interventions
Sponsors
St. Antonius Hospital
Eligibility
Inclusion criteria
Inclusion criteria: - 18 years of age or older - Diagnosis of Barrett’s esophagus undergoing surveillance gastroscopy - Signed consent for the use of patient data
Exclusion criteria
Exclusion criteria: - Previous treatment for esophageal neoplasia (endoscopic resection, photodynamic therapy, argon plasma coagulation, radiofrequency ablation) - Referral from other centers with suspected or known dysplasia for assessment and endoscopic intervention - Obvious visible cancers at gastroscopy other than esophageal adenocarcinoma (i.e. gastric cancer, or esophageal squamous cell carcinoma) - Known dysplasia or intensified endoscopic surveillance because of previously diagnosed dysplasia - Prior esophagectomy - Active esophagitis LA grade C or higher, precluding endoscopic biopsies (patients can be included after adequate treatment) - Esophageal varices precluding endoscopic biopsies - Coagulation disorders precluding endoscopic biopsies - Allergy to acetic acid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall neoplasia detection rate (defined as the percentage of patients with either targeted or standardized random biopsies containing LGD, HGD or EAC). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Neoplasia detection rate stratified by degree of neoplasia in biopsies (LGD, HGD, EAC). 2. Neoplasia detection rate in of targeted biopsies only (defined as the percentage of patients with targeted biopsies containing LGD, HGD and EAC). 3. Duration of endoscopy. | — |
Contacts
Public ContactIlse Beaufort
St. Antonius Ziekenhuis
Outcome results
None listed