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OLVG Food Allergy Growth Study

The Amsterdam food allergy growth study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON25057
Enrollment
200
Registered
2021-01-02
Start date
2020-11-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergy

Interventions

none

Sponsors

OLVG
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Any child between 0-18 years of age with a confirmed food allergy and elimination diet: 1. Confirmed through either skin prick testing/specific IgE testing which has led to a recommendation for the elimination of these allergens from the diet; 2. Confirmed through a food challenge; 3. Confirmed through an elimination diet followed by re-introduction at home ; 4. Children born à term (between 37 and 42 weeks of gestation).

Exclusion criteria

Exclusion criteria: 1. Children with non-allergic co-morbidities – Down’s Syndrome, cerebral palsy etcetera; 2. Children where it is not possible to measure growth parameters; 3. Children where food allergies have not been confirmed; 4. Not able to speak and write in Dutch or English properly; 5. Preterm children: birth before 37 weeks of gestation.

Design outcomes

Primary

MeasureTime frame
Height-for-age: Most recent height/length, head circumference and weight are derived from the medical record, using calibrated digital scales, length board or height board and a non-stretchable tape measure measured by medical staff during routine medical visits at the paediatric departments OLVG Oost and West.

Secondary

MeasureTime frame
Within 4 weeks after handing in signed informed consent: • Weight-for-height, weight-for-age, and BMI SDS are calculated using ethnic adjusted standard deviation scores (SDS) by the study dietitian Mooij-Nieberg, which will be obtained by using Dutch growth standards (3,20) as well as the standards provided by the World Health Organisation for growth (18,19); • The association between patient characteristics and possible contributing factors for poor growth; Patient characteristics and risk factors will be obtained by the study dietitian Mooij-Nieberg, using telephone questionnaires as pointed out in 3.5.2; • The association between calprotectin and growth; A stool sample will be collected at home and sent to OLVG hospital. Calprotectin will be analyzed In batches at Hanze University of Applied Sciences, department of Life Sciences, as pointed out In 3.5.3.; • The association between calprotectin and growth in children with diagnosed food allergies; Patients or their caregivers will fill in 3x an online 24-hour recall diary about all foods and drinks consumed. These will be checked for completeness by the study dietitian Mooij-Nieberg.

Contacts

Public ContactBerber Vlieg-Boerstra

OLVG

b.vlieg-boerstra@olvg.nl0620965612

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)