Unexplained subfertility.
Conditions
Interventions
After informed consent had been given, couples were randomly allocated between IUI with COH and expectant management for six months.
Couples allocated to IUI with COH started treatment in the next cy
Sponsors
OFO-project
t.a.v. B.W. Mol
Academic Medical Center
Center of Reporductive medicine, H4-213
Postbus 22660
1100 DD Amsterdam
Phone: 0031205663857
Fax: 0031206963489
e-mail: ofoproject@amc.uva.nl or b.mol1@chello.nl
Eligibility
Inclusion criteria
Inclusion criteria: All subfertile couples in whom no reason is found during the basic fertility work-up for their subfertility and in whom their spontaneous pregnancy chance in the next year, calculated by the results of the basic fertility work-up, is between 30% and 40%.
Exclusion criteria
Exclusion criteria: All couples in whom a reason is found for their subfertility or who are having an other prognosis calculated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint was ongoing pregnancy within six months. Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies. | — |
Contacts
Public ContactP. Steures
Academic Medical Center (AMC), Center of Reproductive medicine, OFO-project, H4-213, P.O. Box 22660
Outcome results
None listed