Colorectal, neoplasia, adenomas, Colonoscopy, Imaging, Detection, classification Dutch: colon, neoplasie, adenomen, coloscopie, imaging, detectie
Conditions
Interventions
ETMI tandem colonoscopy: High resolution endoscopy (HRE) followed by autofluorescence imaging (AFI).
Conventional colonoscopy: Standard resolution colonoscopy followed by standard resolution colonosco
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Patients (>18 years) undergoing colonoscopic surveillance because of: a. history of adenomatous polyps. b. history of CRC. c. Hereditary Non-Polyposis Colorectal Cancer d. family history of CRC/adenomas
Exclusion criteria
Exclusion criteria: 1. Poor bowel preparation; 2. Familial Adenomatous Polyposis, attenuated FAP, MYH associated polyposis or hyperplastic polyposis; 3. History of inflammatory bowel disease; 4. Presence of conditions precluding histological sampling of the colon (e.g. coagulation disorders, anticoagulant therapy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of adenomas detected by ETMI versus conventional colonoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of adenomas detected by HRE versus conventional colonoscopy; 2. Miss rate of HRE as followed by AFI (additional yield of AFI); 3. Accuracy of NBI and AFI in discriminating non-neoplastic from neoplastic lesions (Kudo classification and color) | — |
Contacts
Public ContactEvelien Dekker
Academic Medical Center (AMC) Department of Gastroenterology and Hepatology P.O. Box 22660
Outcome results
None listed