Argenine suppletie om de reperfusie schade te verminderen en doorbloeding te verbeteren na vrije weefsel transplantaties.

L-Arginine and reperfusion injury in free flap surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25004

Enrollment

Registered

2009-01-13

Start date

2003-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reperfusion injury, Arginine, free flap surgery

Interventions

Patients received intravenously one liter of either L-arginine (verum group, 30 g L-arginine-HCl / 1L 0.9% NaCl) or an Alanine (placebo group, 25.2 g Alanine / 1L 0.9% NaCl) during a 24 hour period.

Eligibility

Inclusion criteria

Inclusion criteria: All patients with free TRAM flap breast reconstruction.

Exclusion criteria

Exclusion criteria: Previous midline laparotomy.

Design outcomes

Primary

Measure	Time frame
Partial flap loss (result of insufficient bloodflow).	—

Secondary

Measure	Time frame
Laser doppler flow (microcirculation measurement).	—

Contacts

Public ContactR.R.W.J. Hulst, van der

P. Debeyelaan 25

rvh@spch.azm.nl+ 31 433875624

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)