Oral and gastric contribution to satiety.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON24983

Enrollment

Registered

2010-01-20

Start date

2010-02-15

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating behaviour

Interventions

Oral and gastric stimulation: 1. Oral: 1 min (low) or 8min (high) modiefied sham feeding

2. Gastric: infusion of 100ml (low) or 800ml (high) of a cake solution into the stomach with a naso-gastric tube.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Gender: male; 2. Age: ≥ 18 years and ≤ 40 years; 3. BMI: ≥ 20 and < 25 kg/m2; 4. Stable body weight (change of < 2 kg body weight in last month); 5. Good physical and mental health as judged by the participant himself.

Exclusion criteria

Exclusion criteria: 1. Smoking or drug use; 2. Gastro-intestinal diseases; 3. Diabetes, thyroid diseases or any other endocrine disorders; 4. Lack of appetite for any reason; 5. Restraint eating DEBQ score ≥ 2.26 (above average) [3]; 6. Hypersensitivity or food allergy for products used in this study, that are present in the cake; 7. Unsuccessful placement of the naso-gastric tube at the training visit; 8. Intolerance to placement of the naso-gastric tube or to the intra-gastric infusion of liquid food at the training visit; 9. Recovery of the test product after shamfeeding < 85% (dry mass) at the training visit; 10. Pleasantness rating of the ad libitum test meal offered during training < 40 mm (100 mm VAS); 11. Currently participating or having participated in another clinical trial at the Division of Human Nutrition during the last 3 months prior to the beginning of this study; 12. Taking any medication; 13. Problems with respiratory tract, such as hyperventilation, asthma or bronchitis, that can cause problems when the naso-gastric tube is inserted; 14. Working at, or doing an MSc thesis at the Division of Human Nutrition.

Design outcomes

Primary

Measure	Time frame
Subsequent food intake, as measured with ad libitum lunch intake 30 minutes after start of the oral and gastric stimulation.	—

Secondary

Measure	Time frame
Subjective feeling so satiety as measured with a Visual Analogue Scale (VAS).	—

Contacts

Public ContactAnne Wijlens

PO Box 8129

anne.wijlens@wur.nl+31 (0)317 489369

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)