A multi-center double-blind randomized controlled trial of two media for the in vitro culture of human preimplantation embryos.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON24976

Enrollment

784

Registered

2009-09-01

Start date

2009-01-09

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subfertility

Interventions

Ovarian hyperstimulation, oocyte retrieval and oocyte fertilization will be performed using standard procedures. In the experimental arm, all oocytes and resulting embryos will be cultured in G5-mediu

Eligibility

Inclusion criteria

Inclusion criteria: Subfertile couples undergoing IVF (in vitro fertilization) or ICSI (intracytoplasmatic sperm injection).

Exclusion criteria

Exclusion criteria: 1. Couples undergoing a PGD cycle; 2. Couples for which IVF is used to prevent the transmission of HIV; 3. Couples undergoing a modified natural cycle.

Design outcomes

Primary

Measure	Time frame
Primary outcome measure will be live birth rate per patient after one year of treatment.	—

Secondary

Measure	Time frame
Secondary outcome measures will be embryo quality, clinical pregnancy rate, ongoing pregnancy rate, miscarriage rate, time to pregnancy, birth weight and percentage of children with congenital abnormalities.	—

Contacts

Public ContactSebastiaan Mastenbroek

Academic Medical Center (AMC), Center For Reproductive Medicine, P.O. Box 22660

S.Mastenbroek@amc.uva.nl+31 (0)20 5663090

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)