"Chronisch Obstructief Pulmonale Aandoening (COPD)" "Chronic Obstructive Pulmonary Disease (COPD)"
Conditions
Interventions
Metronome-paced tachypnea.
Sponsors
Medisch Spectrum Twente Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Mild-severe stable COPD; 2. Ability to read and speak Dutch; 3. Informed consent; 4. An age of atleast 40 years old and not older than 80.
Exclusion criteria
Exclusion criteria: 1. GOLD stage IV; 2. COPD exacerbation 3. Rapid decline of clinical course; 4. Use of a wheelchair; 5. Use of longterm oxygen therapy; 6. A history of severe astma; 7. Any medical condition that limits the daily activity; 8. Serious psychiatric comorbidity; 9. Participation in a COPD rehabilition program in the previous 3 months; 10. Serious comorbidity with a reduced life expectancy; 11. Restrictive lungdisease (TLC < 80%); 12. A chronic lungdisease other than COPD; 13. A history of myocardial infarction, heartfailure or cardiac arrhythmia in the previous 6 months that requires treatment; 14. Inability to travel to hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of dynamic hyperinflation (ΔIC/s): Hyperinflation is defined as an increase in the end-expiratory lungvolume (EELV). A decrease in inspiratory capacity (IC) is used as a substitute for the increased EELV. This is based on the assumption that the total lungcapacity (TLC) has to remain constant. An increase of the EELV has to result in a decrease of the IC, because the sum of these parameters composes the TLC (EELV+IC=TLC). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Rate of recovery after DH (ΔIC/s); 2. The degree of DH (ΔIC); 3. Activity outcome IMA. To measure physical activity a smartphone (HTC Desire/ HTC Desire S) and a motion sensor (ProMove 3D wireless inertial sensor, Inertia Technology) will be used. The motion sensor is a triaxial accelerometer that measures acceleration. The average value of the three axes of motion are than calculated and converted into activity outcome IMA. The outcome measure is calculated with the method of Bouten et al., that can be highly related to energy expenditure. A change of velocity occurs when a person starts to move and stops to move. The motion sensor connects through a Bluetooth-connection with a smartphone. Daily activity data is subsequently memorized as activity outcome IMA on the hard drive of the smartphone. The motion sensor is being carried on the patient’s belt and the smartphone is being kept near the patient. This method has been approved by the Medical research ethics committee of the Medisch Spectrum Twente Hospital in Enschede. 4. Borgscale (1-10) before and after MPT. | — |
Contacts
Public ContactP.D.L.P.M. Valk, van der
Medisch Spectrum Twente Hospital Department of Pulmonology PO Box 50.000
Outcome results
None listed