Longaandoeningen welke kunstmatige beademingen behoeven Respiratory failure in need of mechanical ventilation
Conditions
Interventions
None listed
Sponsors
University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: - all patients who require mechanical ventilation aged 0-18 years - patients should be able to trigger the ventilator with a pre-set flow trigger of 1 liter/min
Exclusion criteria
Exclusion criteria: - premature birth with gestational age corrected for post-conceptional age less than 40 weeks - congenital or acquired neuromuscular disorders - congenital or acquired central nervous system disorders with depressed respiratory drive - severe traumatic brain injury (i.e. Glasgow Coma Scale < 8) - congenital or acquired damage to the phrenic nerve - congenital or acquired paralysis of the diaphragm - use of neuromuscular blockade - chronic lung disease - severe pulmonary hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of patient-ventilator-asynchrony. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Level and time course of incidence PVA. • Time course of distribution of type of PVA. • Level and time course of diaphragm EMG. • Level and time course of intercostals EMG. • Level and time course of phase angle distribution. | — |
Contacts
Public ContactR.G.T. Blokpoel
Department of Paediatric Intensive Care Beatrix Children’s Hospital University Medical Center Groningen
Outcome results
None listed