High risk patients on (orthopaedic) surgical wards
Conditions
Interventions
1. A team of hospital pharmacists-clinical pharmacologists and internists-clinical pharmacologist will train participating hospital pharmacists to perform intensive pharmacovigilance in high-risk pati
2. Selection of high risk patients by a screening method
3. Intensive pharmacovigilance in high risk patients: Structured medication review will be performed combining clinical data and the list of current medication of the patient
4. Less intensive pharmacovigilance of low risk patients: Automatically finishing of alerts, which are known to be without harm for low risk patients (90%), without intervention of the hospital pharma
5. Education program for physicians and physician assistants: The most important pharmacologic items will be discussed and national and hospital guidelines, related to these subjects will be explained
Sponsors
Canisius Wilhelmina Hospital/
Department Clinical Pharmacy
Radboud University Nijmegen Medical Center
Mevr. J.M. Bos, hospital pharmacist
Dr. C. Kramers, internist-clinical pharmacologist
Eligibility
Inclusion criteria
Inclusion criteria: All patients admitted to wards of surgery and orthopaedic surgery of two hospitals during the study period, consisting of 6 months usual care and 6 months intervention (sample size per group is 5300).
Exclusion criteria
Exclusion criteria: N/A
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unintended drug related problems due to prescription errors, that lead to death, disability, increased length of hospital stay and readmission. Outcomes are judged by opinions of a panel of experts. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Serious prescription errors; 2. Non-serious prescription errors; 3. Guideline adherence. Outcomes are judged by opionions of a panel of experts. A pharmaco-economic evaluation will be performed. | — |
Contacts
Public ContactJ.M. Bos
Canisius Wilhelmina Hospital Department Clinical Pharmacy PO box 9015
Outcome results
None listed