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The impact of collagen peptide versus free amino acid ingestion on myofibrillar and connective tissue protein synthesis rates at rest and during recovery from exercise

The impact of collagen peptide versus free amino acid ingestion on myofibrillar and connective tissue protein synthesis rates at rest and during recovery from exercise

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON24853
Enrollment
45
Registered
2021-02-03
Start date
2021-03-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

n.a.

Interventions

Participants (n=15 per group) will perform unilateral resistance exercise followed by the ingestion of either 30 g of collagen peptides, 30 g free amino acids (matching the profile of collagen peptide

Sponsors

Maastricht University and Tessenderlo Group NV
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Males and females - Aged between 18-35 years - Healthy, recreationally active (participating in recreational sports activities = 3 times per week) - BMI 18.5 - 30 kg/m2 - No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner)

Exclusion criteria

Exclusion criteria: - Pregnant - Third generation oral contraceptives - Hormone replacement therapy - Musculoskeletal disorders - Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications). - Participation in any structured regular exercise program - Chronic use of gastric acid suppressing medication or anti-coagulants - Unstable weight over the last three months - Pathologies of the gastrointestinal tract - Blood donation in the past 2 months

Design outcomes

Primary

MeasureTime frame
Myofibrillar and connective tissue protein synthesis rates.

Secondary

MeasureTime frame
Plasma amino acid concentrations and body composition.

Contacts

Public ContactLuc van Loon

Maastricht University

l.vanloon@maastrichtuniversity.nl+31433881379

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)