At-risk mental state for psychosis (ARMS) or first episode psychosis (FEP)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 15-65 years 2. Mental competence 3. Sufficient command of the Dutch language to understand and follow instructions 4. PQ score >6 5. An ARMS or FEP as assessed by the CAARMS
Exclusion criteria
Exclusion criteria: 1. Presence of drug/alcohol dependence or abuse (based on sections K and L of the Mini International Neuropsychiatric Interview) as primary diagnosis. Exception: early remission criterion according to DSM V is met (“After full criteria for substance/alcohol use disorder were previously met, none of the criteria for substance/alcohol use disorder have been met for at least three months but for less than twelve months (with the exception that the criterion A4, "craving, or a strong desire or urge to use drug in question", may be met.”) 2. Severe endocrine, cardiovascular or brain disease 3. Diagnosis of organic psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study’s main parameters are distress related to psychotic experiences, general and social functioning, and (sub-)clinical symptoms as measured with questionnaires and interviews. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are stress-reactivity, reward-experience, and overall positive affect, as measured with the experience sampling method (ESM). | — |
Contacts
Center for Contextual Psychiatry, Dept. Neurosciences, KU Leuven