pediatric postoperative cardiac surgery patients, red blood cell transfusion, morbidity, nososcomial infection, MBL, venous saturation pediatrische postoperatieve cardiochirurgische patienten, erytrocytentransfusie, morbiditeit, nosocomiale infecties, MBL, veneuze saturatie
Conditions
Interventions
After inclusion the patients are randomised in two groups (restrictive and liberal transfusion policy). The transfusion triggerpoint for the restrice group is set at a hemoglobin of 5 mmol/L versus 6,
Sponsors
D.A.H. de Gast-Bakker, kinderarts-intensivist, LUMC
IC centrum, LUMC, Prof. Dr. L.P.H.J. Aarts
Sanquin bloedbank zuid-west Nederland (Dr.L.M.G. van de Watering)
Eligibility
Inclusion criteria
Inclusion criteria: Pediatric patients with a non-cyanotic congenital heart defect (>3 kg, >6 weeks and < 6 years) undergoing cardiac surgery.
Exclusion criteria
Exclusion criteria: 1. Neonates; 2. Underlying hematological disease (hemoglobinopathy); 3. Patients participating in another study that may interfere with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in red blood cell transfusion and the morbidity related to the transfusion (expressed as ventilator days, length of PICU and hospital stay, nosocomial infections). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Can continuous venous saturation monitoring guide the transfusion policy? 2. How usefull are continuous oxygen saturation measurements? 3. What is the role of mannose binding lectin (MBL) and the development of nosocomial infections in transfused pediatric postoperative cardiac surgery patients. | — |
Contacts
Public ContactD.A.H. Gast-Bakker, de
Leids Universitair Medisch Centrum Postbus 9600
Outcome results
None listed