Premedication in children scheduled for minor elective procedures such as inguinal hernia repair, circumcision and orchidopexy under general anaesthesia. Keywords: premedication,children midazolam, dexmedetomidine
Conditions
Interventions
Children will be randomly allocated into two groups:
1. Group I - 0.25 mg/kg midazolam will be given sublingually (drug to be retained in the mouth without spitting or swallowing) by asking the chil
2. Group II- 1.5 µg/kg dexmedetomidine will be given sublingually (drug to be retained in the mouth without spitting or swallowing) by asking the child to place the tip of the tongue to the back of up
Sponsors
Dept of Anaesthesiology, Pain & Perioperative Medicine
Sir Ganga Ram Hospital, New Delhi ,India
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children with ASA physical status I or II; 2. Age between 1 and 12 years; 3. Children undergoing elective inguinall hernia repair, orchidopexy or circumcision, under general anaesthesia and caudal block.
Exclusion criteria
Exclusion criteria: 1. Known allergy or hypersensitive reaction to midazolam or dexmedetomidine; 2. Liver or renal dysfunction; 3. Cardiac arrhythmia or congenital heart disease; 4. Mental retardation; 5. Use of enzyme inducing medication e.g. phenobarbitone; 6. Upper respiratory tract infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Behaviour and sedation status of the child during separation from the parent and at induction of anaesthesia; 2. Mask acceptability of the child at induction of anaesthesia; 3. Perioperative changes in heart rate and blood pressure; 4. Behaviour status of the child at time of wake up from anaesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to discharge from post-anaesthesia care unit (PACU). | — |
Contacts
Public ContactDeepanjali Pant
Dept of Anaesthesiology, Pain & Perioperative Medicine Sir Ganga Ram Hospital, New Delhi, India
Outcome results
None listed