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Prevention of Osteoarthritis in Overweight Females.

Prevention of knee osteoarthritis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON24692
Enrollment
100
Registered
2006-05-11
Start date
2005-12-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

Intervention A: a tailor-made intervention to reduce weight under direction of dieticians of homecare Rotterdam for one year. The control group will not receive this active intervention to reduce we

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Women aged 50-60 years with overweight (BMI of 27 or more).

Exclusion criteria

Exclusion criteria: 1. Knee OA; 2. Knee pain indicating knee OA; 3. Radiological signs indicating knee OA (Kellgren-Lawrence index of 2 or more); 4. Positive for knee OA according to the ACR criteria for knee OA; 5. Presence of severe co-morbidity; 6. Pacemaker; 7. Already use of glucosaminesulphate; 8. Not being able to communicate in the Dutch language.

Design outcomes

Primary

MeasureTime frame
1. Percentage participants per group showing a reduction of 5kg and/or 5% decrease at one year follow-up compared to baseline weight; 2. Percentage women compliant to the interventions in the study; 3. Percentage lost to follow-up after one year; 4. Percentage participating person of eligible persons.

Secondary

MeasureTime frame
1. Difference in intermediate outcomes between intervention group A and control group A at one year follow-up; 2. Difference in intermediate outcomes between intervention group B and control group B at one year follow-up; 3. Change and variation in change in intermediate outcomes between baseline and one year follow-up.

Contacts

Public ContactLiane Augustinus

Afdeling Huisartsgeneeskunde, kamer Ff-314, Erasmus MC, P.O. Box 1738

l.augustinus@erasmusmc.nl+31 (0)10-4088192

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)