cardiac surgery
Conditions
Interventions
None
Sponsors
UMCG
Eligibility
Inclusion criteria
Inclusion criteria: •In order to be eligible to participate in this study, a subject must meet all of the following criteria: Scheduled for elective cardiac coronary surgery, and booked for routine clinical assessment on the cardiosurgical preoperative screening unit. •Age 55 years and older •Able to stand and walk independently •Able to participate in the online screenings module for cognitive function (ie able to operate a computer touch pad or mouse, and to read large text on a computer screen). •They should be prepared to allow a researcher to visit them at home 3 months after their operation. •Patients need to be able to perform the handgrip strength test on both sides.
Exclusion criteria
Exclusion criteria: •A potential subject who meets any of the following criteria will be excluded from participation in this study: Extended postoperative ICU stay is expected. •Inability to understand or read Dutch instructions •Recent history of depression or severe anxiety •History of dementia or other neurological disorders •History of stroke, or other severe cerebrovascular insults •Patient is not able to perform get-up-and-go test or any of the other tests
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary parameters are: -Physical activity (Squash questionnaire) -Muscle strength (poundsforce) baseline, after 3-4 days post IC and after 3 months -Incidence of cognitive dysfunction at 3 months (compared to baseline) -Results of get-up-and-go test (secs) baseline and after 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Analysis of factors associated with POCD: Multiple binary logistic regression analysis will be performed to determine the relative strengths of association between potential factors (age, baseline cognitive function, physical inactivity, baseline inflammatory markers) and POCD. 2.Correlation analysis and ANOVA after dichotomisation of physical activity and fitness with morbidity and outcome variables | — |
Contacts
Public ContactR. Spanjersberg
Hanzeplein 1
Outcome results
None listed