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Prescription of Antibiotics in pRimary CAre

Prescription of Antibiotics in pRimary CAre; a focus on immigrant communities

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON24668
Enrollment
58
Registered
2021-05-02
Start date
2021-03-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

We focus on the number of dispensed antibiotics, qualifying for respiratory tract infections, that are prescribed by GPs. Important to note is that the unit of analysis are the GPs and not the patients.

Interventions

The intervention for the GPs will consist of three different components: - An E-learning focused on intercultural skills with 4 lessons of 10-15 minutes each
- An evening training session (3.5 hours) in which GPs will be taught intercultural skills, discuss video-taped consultations with intercultural doctor-patient interactions, and practice the newly lea
- Use of patient materials (written information and an animation movie that will be presented on the website Thuisarts.nl) for immigrant patients in their own language, to be used during consultation.

Sponsors

Erasmus MC, University Medical Center Rotterdam, and the Municipal Health Service of Rotterdam-Rijnmond.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Dutch GPs/locums, with a specific focus on GPs who are located in or around Rotterdam, Amsterdam, The Hague and Utrecht.

Exclusion criteria

Exclusion criteria: - Locums who work at diverse practices. - Locums who work at one practice but who do not prescribe under their individual prescriber code. - GPs from whom the individual prescriber code cannot be identified in the data.

Design outcomes

Primary

MeasureTime frame
Our primary outcome is the number of dispensed courses of antibiotics qualifying for respiratory tract infections, per 1000 registered patients. For eligible antibiotics, we selected all first and second choice antibiotics that qualify for respiratory tract infections according to the Dutch antibiotic guidelines and expert opinion. This produced the following selection of eight antibiotics: Doxycycline (J01AA02), Amoxicillin (J01CA04), Augmentin (J01CR02), Phenoxymethylpenicillin (J01CE02), Sulphonamides with trimethoprim inclusive derivatives (J01EE), Macrolides (J01FA), Moxifloxacin (J01MA14), and Pheneticillin (J01CE05). To evaluate the effect of the intervention, we will perform a one-way ANCOVA (analysis of covariance) in which we statistically control for the number of dispensed antibiotics at baseline and the differences between the intervention and the control group. The number of dispensed antibiotics at baseline for both groups will be compared with the number of antibiotics during the 6 months following the intervention. We will perform our analysis according to both an intention-to-treat (ITT) and a per-protocol (PP) analysis in which the GPs in the intervention arm who did not follow the training session, will be removed from the analysis.

Secondary

MeasureTime frame
The total number of dispensed courses of antibiotics for all infections (regardless of the origin), per 1000 registered patients.

Contacts

Public ContactDominique Lescure

Erasmus MC

dla.lescure@rotterdam.nl0618293349

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)