Healthy term infants
Conditions
Interventions
Infants that are on full formula feeding will join the formula fed group, fully breastfed infants will join the breastfeeding reference group.
On the examination day 2 blood samples will be withdraw
Sponsors
Danone Research - Centre for Specialised Nutrition / UMC Groningen
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy and full-term infants (gestational age > 37 and < 42 weeks); 2. Birth weight within the normal range for sex and gestational age (10th to 90th percentiles according to locally applicable growth charts); 3. 60 days of age or older; 4. Body weight appropriate for the age of 8 weeks and sex (10th to 90th percentiles according to locally applicable growth charts); 5. Written informed consent of both parent(s)/legal guardian(s).
Exclusion criteria
Exclusion criteria: 1. Infants with known congenital diseases or malfunctions e.g. gastrointestinal malformations, haemophilia; 2. Infants having received medical treatment with antibiotics and/or pain medication like paracetamol which may be included in cough syrup or other mixtures) within 4 days before examination; 3. Infants with abnormal growth (too slow or too fast weight gain) within the 10th to 90th percentiles of locally applicable weight-for-age charts for either boys or girls; 4. Infants needing a special diet other than standard cow's milk-based infant milk formula; 5. Infants having a mother suffering from known hepatitis B, HIV, high blood-pressure, hyperlipidaemia or diabetes; 6. Infants having an overweight (BMI > 27) mother prior to her first pregnancy; 7. Infants with any historical participation in any other study involving investigational or marketed products; 8. Investigator's uncertainty about the willingness or ability of the parent(s)/legal guardian(s) to comply with the protocol requirements and instructions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial total plasma triglyceride levels at baseline and 30, 60, 90, 120, 180 or 240 minutes after baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in total plasma triglyceride levels between 2 feeding regimen (formula feeding vs. breastfeeding), measured at baseline and 30, 60, 90, 120, 180 and 240 minutes after baseline. | — |
Contacts
Public ContactStefanie Schoen
Nutricia Research BV Uppsalalaan 12
Outcome results
None listed