Exercise induced asthma/ inspanningsastma. Inspiratory airflow obstruction/ inspiratoire luchtwegobstructie.
Conditions
Interventions
Two exercise challenge test (older children perform this test on a treadmill, younger children on a jumping castle). 15 minutes prior to the test children inhale either 200ugr salbutamol or a placebo.
Sponsors
Medische Spectrum Twenten
Eligibility
Inclusion criteria
Inclusion criteria: - Clinical history of EIB. - Age 8 till 16 years old. - Ability to jump or run and perform reproducible lung function tests, i.e. coefficient of the predicted value variation in 3 of 5 consecutive measurements < 5%.
Exclusion criteria
Exclusion criteria: - Exacerbation in the last 4 weeks prior to the ECT (hospital admission or use of systemic corticosteroids). - Use of long acting bronchodilators 24 hours before testing. - Use of short acting bronchodilators 8 hours before testing. - Use of leukotriene antagonists 24 hours before testing. - Other pulmonary or cardiac disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The protective effect of a single regular dose of salbutamol compared with a placebo against inspiratory airflow obstruction in asthmatic children aged 8 till 16 years old. | — |
Secondary
| Measure | Time frame |
|---|---|
| The relation between the protective effect of salbutamol against inspiratory airflow obstruction and EIB. | — |
Contacts
Public ContactR. Visser
Medisch Spectrum Twente Departement of pediatrics Haaksbergerstraat 55
Outcome results
None listed