Central Sensitization and Physical Functioning in patients with Chronic Low Back Pain

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON24502

Enrollment

100

Registered

2018-04-16

Start date

2017-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal disorders Chronic low back pain Central sensitization Physical functioning

Interventions

The study is designed as close as possible to ‘care as usual’ for the patients. Patients follow regular procedures according to Pain Rehabilitation team of the Center for Rehabilitation of the UMCG.

Eligibility

Inclusion criteria

Inclusion criteria: - Mentally competent adults between 18 and 65 years of age. - Referred to Pain rehabilitation with chronic low back pain (without radiation below the knee) as primary diagnosis. - Admitted to Pain rehabilitation according to the Pain rehabilitation guidelines. - Voluntarily signed written informed consent.

Exclusion criteria

Exclusion criteria: - Unwillingness to participate in the study. - No or not sufficient understanding of Dutch language, and/or incapacity to follow instructions. - Manifest neuralgia; Pregnancy; Psychiatric disorders or other relevant co-morbidities. - Specific contraindications of the tests according to the center for rehabilitation guidelines.

Design outcomes

Primary

Measure	Time frame
Central Sensitization measurements: - Bedside Examination (BSE): DFNS protocol. - Quantitative Sensory Test (QST): NASQ protocol. - Heart-Rate Variability (HRV): 5 min Heartmath protocol. - Central Sensitization Inventory (CSI): questionnaire in Dutch. Physical Functioning measurements: - Lift test: FCE WorkWell protocol. - Cardiopulmonary Exercise Test (CPET): . - Accelerometer: 7 days. Questionnaires: - Work Ability (WAS). - Pain Disaability (PDI). - Physical Functioning (Rand36-PF).	—

Measure

Time frame

Central Sensitization measurements: - Bedside Examination (BSE): DFNS protocol. - Quantitative Sensory Test (QST): NASQ protocol. - Heart-Rate Variability (HRV): 5 min Heartmath protocol. - Central Sensitization Inventory (CSI): questionnaire in Dutch. Physical Functioning measurements: - Lift test: FCE WorkWell protocol. - Cardiopulmonary Exercise Test (CPET): . - Accelerometer: 7 days. Questionnaires: - Work Ability (WAS). - Pain Disaability (PDI). - Physical Functioning (Rand36-PF).

—

Secondary

Measure	Time frame
Pain characteristics: Intensity - VAS; Response to exercise - PRQ. Patients Characteristics: Age, Sex, BMI (Height, Weight), Nationality, Educational level, Employment Status, Pain location, Psychological traits (Catastrophizing - PCS, Injustice - IEQ, and Symptoms - BSI). Test characteristics: patient and assessor perceived exertion during capacity tests - Borg CR-10 and RPE.	—

Contacts

Public ContactJ. Ansuategui Echeita

University of Groningen Department of Rehabilitation Medicine, Center for Rehabilitation, University Medical Center Groningen,

j.ansuategui.echeita@umcg.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Mar 3, 2026