subfertiliteit subfertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. All couples with unexplained, cervical factor or male subfertility, with an indication for IUI; 2. All couples should have undergone an infertility work up including at least an hysterosalpingogram (HSG); 3. Unexplained subfertility will be diagnosed when ovulation is confirmed with a biphasic BTC and / or midluteal progesterone determination and HSG and / or laparoscopy have confirmed tubal patency at both sides; 4. In case of male factor the male partners should have semen analyses with a yield of > 2 million spermatozoa, but less than 10 million spermatozoa, after processing; 5. Subfertility due to cervical factor will be diagnosed when negative, well-timed postcoïtum tests are found.
Exclusion criteria
Exclusion criteria: 1. Cycles with a yield of 12 IU IU/L) will be excluded as well.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate per couple. Ongoing pregnancy is defined as an intrauterine pregnancy showing a normal developing foetus with positive heartbeat 10 weeks following IUI. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Ongoing pregnancy rate per cycle; 2. Pregnancy rate per couple and per cycle; 3. Cumulative pregnancy rate per couple; 4. Multiple gestation rate per ongoing pregnancy; 5. Miscarriage rate per couple. | — |
Contacts
VU University Medical Center, IVF center, P.O. Box 7057