Prognostic value of pretreatment imaging parameters for recurrent laryngeal and hypopharyngeal carcinoma after primary radiotherapy; a retrospective study.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON24461

Enrollment

500

Registered

2021-01-13

Start date

2021-01-13

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Larynx and hypopharynx carcinoma

Interventions

Radiotherapy with or without chemotherapy

Eligibility

Inclusion criteria

Inclusion criteria: Patients with larynx or hypopharynx carinoma primarily treated with radiotherapy with curative intent with or without additional chemotherapy. Treated in UMC Utrecht in the period of January 2008 and March 2020. Follow-up of at least 2 years or until recurrence. Available MRI imaging of the tumor site is made within 4 weeks before the start of the radiotherapy treatment.

Exclusion criteria

Exclusion criteria: History of carcinoma at the time of diagnosis. Distant metastasis or second primary tumours at time of diagnosis.

Design outcomes

Primary

Measure	Time frame
The effect of imaging variables (e.g. apparent diffusion coefficient, tumor volume, and dynamic contrast enhanced MRI variables) on treatment outcome.	—

Secondary

Measure	Time frame
The effect of clinical variables (e.g. smoking status and tumor stage) on treatment outcome	—

Contacts

Public ContactMarielle Philippens

University Medical Center Utrecht

m.philippens@umcutrecht.nl+31646919474

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)