The value of CTPET scans for the prediction of response after treatment in rectal cancer.

Evaluation of CTPET imaging in the prediction of pathologic complete response after chemoradiotherapy in locally advanced rectal cancer.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON24449

Enrollment

500

Registered

2010-01-14

Start date

2004-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pathologic complete response, prediction, rectal cancer, machine learning, chemoradiotherapy, PET

Interventions

1. FDG-PET imaging (pretreatment)

2. Blood sampling (facultative)

3. FDG-PET imaging (posttreatment, facultative).

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histological proven rectal cancer; 2. Only primary tumors; no recurrences; 3. Only concurrent chemoradiotherapy treatment; 4. 18 years or older.

Exclusion criteria

Exclusion criteria: 1. No adenocarcinoma histology; 2. History of prior pelvis radiotherapy.

Design outcomes

Primary

Measure	Time frame
Pathologic complete response, defined by ypT0N0 stage extracted from pathologic reports.	—

Secondary

Measure	Time frame
1. Local control; 2. Distant metastases; 3. Survival; 4. Relapse free survival; 5. Metastases free survival.	—

Contacts

Public ContactRuud Stiphout, van

Dr. Tanslaan 12

ruud.vanstiphout@maastro.nl+31 (0)88 4455666

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)