Effects of fingolimod on advanced brain measures and clinical measures in multiple sclerosis

Effects of fingolimod on functional brain adaptation and clinical measures in multiple sclerosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON24446

Enrollment

Registered

2014-06-23

Start date

2014-08-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multiple sclerosis, functional magnetic resonance imaging, cognition, functional brain adaptation multiple sclerose, functionele MRI, cognitie, functionele brein adaptatie

Interventions

(functional) magnetic resonance imaging and neuropsychological testing

Eligibility

Inclusion criteria

Inclusion criteria: - Subjects should be between 18 and 65 years of age - Subjects should meet the safety criteria to undergo MRI examination - Patients should be diagnosed with RRMS

Exclusion criteria

Exclusion criteria: - Presence or history of psychiatric or neurological disease (for patients: neurological disease other than MS) - Presence or history of drug abuse - For patients: relapse or steroid treatment less than four weeks prior to examination - Insufficient visual acuity and motor skills to perform the fMRI task

Design outcomes

Primary

Measure	Time frame
- Improved neuropsychological test performance - Changed functional MRI/connectivity - Improved cognitive well-being	—

Contacts

Public ContactQuinten Geest, van

VU Medisch Centrum

q.vangeest@vumc.nl020 4448041

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)