Endometrial polyps, Postmenopausal bleeding. In Dutch: Endometrium Poliepen, Postmenopauzaal bloedverlies.
Conditions
Interventions
Eligible patients will be randomly allocated to undergo saline infused sonography (SIS) and outpatient hysteroscopy. All patients will undergo SIS and hysteroscopy independent of the findings during S
Sponsors
Academic Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Women with postmenopausal bleeding and an endometrial thickness of more than 4 mm in whom a malignancy is ruled out by office endometrial sampling.
Exclusion criteria
Exclusion criteria: 1. Women with postmenopausal bleeding during tamoxifen or arimidex treatment; 2. Women with an endometrial sample containing insufficient material for a reliable diagnosis; 3. Women with suspected malignancy after endometrial sampling or cervical cytology.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence of postmenopausal bleeding. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are: 1. What is the added informativeness of SIS in the diagnosis of endometrial polyps using hysteroscopy as a reference standard? 2. What are the costs of transvaginal sonography, SIS and hysteroscopy as well as the costs of recurrent postmenopausal bleeding? | — |
Contacts
Public ContactM.C. Breijer
Meibergdreef 9
Outcome results
None listed