None listed
Conditions
Interventions
Sponsors
Maastricht University
Eligibility
Inclusion criteria
Inclusion criteria: - Aged between 18-35 years - Healthy, recreationally active - Male - BMI < 30 kg/m2
Exclusion criteria
Exclusion criteria: - Smoking - Allergies to milk proteins (whey or casein) - Arthritic conditions - A history of neuromuscular problems - Recent (<1 y) participation in amino acid tracer studies - Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications) - Individuals with gastrointestinal diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is microvascular blood flow expressed in arbitrary units measured in rest, following a bout of resistance-type exercise, immediately following the cold/thermoneutral water bath, and 60 and 180 min following the cold/thermoneutral water bath. Microvascular blood flow is measured with contrast-enhanced ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include femoral artery blood flow expressed as L/min (measured with Doppler ultrasound at the same time points as microvascular blood flow) and L-[ring-13C6]-phenylalanine enrichment in mixed muscle protein expressed as mole percent excess measured with gas-chromatography-combustion isotope ratio mass spectrometry at 4 hours following the cold/thermoneutral water bath. | — |
Contacts
Public ContactMilan Betz
Maastricht University
Outcome results
None listed