Esophagectomy for patients with resectable esophageal cancer and cervical lymph node metastases

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON24304

Enrollment

Registered

2014-05-01

Start date

2014-09-01

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Transthoracic esophageal resection combined with three field lymphadenectomy.

Eligibility

Inclusion criteria

Inclusion criteria: -Histologically proven squamous cell carcinoma, adenocarcinoma or undifferentiated carcinoma of the intrathoracic esophagus. -Surgical resectable carcinoma (T1-4a, N0-3) -Histologically/ cytologically proven resectable cervical lymph node metastases -Age > 18 and < 80 years -European Clinical Oncology Group (ECOG) performance status 0,1 or 2 -Written informed consent

Exclusion criteria

Exclusion criteria: - Distant metastases - Inadequate pulmonary function disabling transthoracic resection - Previous neck dissection

Design outcomes

Primary

Measure	Time frame
Primary outcome is the percentage of overall postoperative complications grade 3b and higher as stated by the modified Clavien-Dindo classification (MCDC).	—

Secondary

Measure	Time frame
Secondary outcomes are mortality, operation related events and postoperative recovery, disease free survival, overall survival and if applicable the location of recurrent disease.	—

Contacts

Public ContactS. Horst, van der

Department of Surgery, G04.228 University Medical Center Utrecht

shorst2@umcutrecht.nl+31 (0)88 755 8074 pager 3479

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)