Freezig of gait in Parkinson's disease
Conditions
Interventions
• The main objective of this study is to assess the functional efficacy of external cueing, provided by Google Glass, on walking performance and occurrence of FOG. For this purpose, we will perform ho
1) in the absence of cueing, 2) in the presence of conservative cueing devices (such as a metronome)
3) in the presence of cueing by Google Glass. We will apply a previously validated algorithm on the data of the activity monitor to detect the occurrence and duration of FOG episodes (Delval et al., 2
Sponsors
Universiteit Twente
Eligibility
Inclusion criteria
Inclusion criteria: • Men/women of age > 18 years with idiopathic Parkinson’s disease, as diagnosed by the UK Brain Bank Criteria (Hughes et al. , 1992). • Written informed consent. • Presence of FOG (defined as a score of 1 on question 1 "Have you experienced FOG in the past month" from the NFOGQ). • Disabling/regular FOG (defined as a score of 3 "Very often, more than one time a day" on question 2 "How often do you experience FOG" from the NFOGQ). • Patients need to use conservative cues in daily life.
Exclusion criteria
Exclusion criteria: • Presence of stroke in history or a psychiatric disease. • Severe visual impairments. • Severe co-morbidity (such as orthopedic problems) limiting ambulation. • Severe cognitive impairments (MMSE<24).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • The statistical design will focus on the comparison of the number of FOG episodes between the three one-week periods with and without cueing. Application of a previously validated algorithm to detect FOG episodes and comparison of the three periods will determine the functional efficacy of the Google Glass on FOG in the home environment. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Evolution of walking activity over days, falls and presence of FOG episodes will be examined with the help of the patients' diaries. • Effect on quality of life (PDQ39), walking speed (10 meter walking test and Timed-Up and Go-test) and activities of daily living (Nottingham Extended Activities of Daily Living Index). • Patients subjective impression of external cueing by Google Glass and conservative cues on a 5 points Likert scale (major impairment - minor impairment - no effect - minor improvement - major improvement). • The Frontal Assessment Battery score will be used as a covariate in all performed analyses. | — |
Contacts
Public ContactJorik Nonnekes
Radboud UMC
Outcome results
None listed