ARDS, Lung injury, Cardiac Surgery, CPB, Ivflammatory response
Conditions
Interventions
none
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients, that are scheduled for all types of elective cardiac surgery, with or without CPB. For the purpose of the study low risk cardiac surgery is defined as CABG with single valve reconstruction or replacement. Complex cardiac surgery is defined as: multiple valves reconstruction or replacement, and/or heart failure surgery (DOR, corcap)
Exclusion criteria
Exclusion criteria: Inability to sign informed consent, less than 18 years old, emergency operations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Length of ICU-stay, length of hospital-stay, ICU-mortality, 30-day mortality | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Prognostic: occurrence of ALI and ARDS, duration of mechanical ventilation, need for renal replacement therapy 2. Etiologic: levels and time course of markers of inflammation and ischemia-reperfusion in relation to the clinical course (such as AlI and ARDS, duration of mechanical ventilation, need for renal replacement therapy, ICU-stay, hospital-stay, ICU-mortality, 30-day mortality) particular in patients following complex heart surgery as opposed to low risk surgery 3. Methodologic: Investigate the value of collecting minimal invasive endobronchial samples in cardiac surgery patients. | — |
Contacts
Public ContactJudith van Paassen
Department of Intensive Care - Location J4-24, LUMC
Outcome results
None listed