BREathprint Variation during Intubation, mechanical ventilation and Anesthesia.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON24277

Enrollment

Registered

2011-02-11

Start date

2011-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated lung injury

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Planned elective surgery (with planned intubation >5h); 2. Informed consent; 3. Anesthesia with intravenous anesthestics.

Exclusion criteria

Exclusion criteria: 1. < 18 years of age; 2. History of any chronic or acute pulmonary condition (asthma, COPD, CF, pulmonary malignancy or acute lung injury); 3. Intubation and mechanical ventilation within the last 7 days.

Design outcomes

Primary

Measure	Time frame
1. Breathprint (exhaled biomarkers) as obtained by electronic nose measurement (Cyranose and ContiNose); 2. Systemic biological markers of oxidative stress and lung injury (e.g. Urin acid, IL-1b, IL-6, IL-8, TNFa en MPO).	—

Contacts

Public ContactLieuwe D.J. Bos

Academic Medical Center, Room G3-228 Meibergdreef 9

l.d.bos@amc.uva.nl+31 (0)20 5666345

Outcome results