feeding tolerance premature infants intermittent feeding semi-continuous feeding voedingstolerantie premature kinderen intermitterend voeden semi-continu voeden
Conditions
Interventions
Bolus intermittent nasogastric feeding
Sponsors
J.B. van Goudoever, MD, PhD
Erasmus MC - Sophia Children's Hospital
University Medical Center
Department of Pediatrics
Division of Neonatology
Dr. Molewaterplein 60
3015 GJ Rotterdam
The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1. Admission to neonatal intensive care unit within 24 hrs after birth; 2. Gestational age under 32 weeks; 3. Birth weight less than 1750 grams.
Exclusion criteria
Exclusion criteria: 1. Simultaneous participation in another trial of which the intervention may influence this trials endpoints; 2. Congenital gastrointestinal obstructions like duodenal atresia, anal atresia, etc.; 3. Any disease entity known to encompass impaired growth other than small gestational age; 4. No informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect on both feeding regimes on feeding tolerance. Primary objective is days to reach full enteral feedings, defined as ¡Ý 120 mL/kg/d. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Secondary objective is number of feeding interruptions, days on total parenteral nutrition and number of apnea episodes per day; 2. To assess somatic growth in both feeding regimes. To evaluate this variable, the following items will be used: days to regain birth weight, rates of weight gain, knemometry and head circumference; 3. To assess complications in both groups measured as catheter related sepsis and necrotizing enterocolitis. | — |
Contacts
Public ContactJ.B. Goudoever, van
Erasmus Medical Center, Sophia Children's Hospital P.O. Box 2060
Outcome results
None listed