neoantal transition, respiratory distress, neonate, caffeïne, breathing, tidal volume
Conditions
Interventions
As soon as possible after birth caffeine 10 mg/kg will be given intravenously. Birth weight will be calculated using estimated fetal weight or the expected weight based on the gestational age.
Caffe
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Infants born in LUMC with a gestational age < 30 weeks of gestation
Exclusion criteria
Exclusion criteria: Infants will be excluded if they are found to have a congenital abnormality or condition that might have an adverse effect on breathing or ventilation, including: congenital diaphragmatic hernia, trachea-oesophageal fistula or cyanotic heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average respiratory minute volume at 7-10 minutes after birth | — |
Secondary
| Measure | Time frame |
|---|---|
| -Average Rate of rise to maximum tidal volume at 7-10 minutes after birth -Time of mask ventilation given -Oxygen saturation and heart rate in the first 10 minutes from birth -Maximal oxygen needed in the first 10 minutes -Total amount of pure oxygen given to the patient (oxygen load) will be calculated taking into consideration birth weight, tidal volume, respiratory rate, fraction of inspired oxygen (FiO2) and timing of stabilisation | — |
Contacts
Public ContactJanneke Dekker
LUMC
Outcome results
None listed