Epigenetic effects of IVF in placental tissue

Epigenetic effects of IVF in placental tissue: a pilot study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON24203

Enrollment

200

Registered

2008-04-25

Start date

2008-05-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IVF pregnancies

Interventions

None. In both groups, placental tissue will be collected after birth and examined for several epigenetic markers

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients pregnant after IVF or ICSI 2. Control group: spontaneous pregnant patients

Exclusion criteria

Exclusion criteria: 1. Twin gestations 2. Delivery before 37 weeks of gestation 3. Pregnancies after fertility treatment other than IVF or ICSI

Design outcomes

Primary

Measure	Time frame
The expression levels of several imprinted genes in placental tissue from spontaneous and IVF pregnancies	—

Secondary

Measure	Time frame
The DNA methylation level of several imprinted genes in placental tissue from spontaneous and IVF pregnancies	—

Contacts

Public ContactE. Nelissen

Academic hospital Maastricht Dept. of Obstetrics and Gynaecology

enel@sgyn.azm.nl+31 (0)43 3875360

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)