Subfertility or infertility
Conditions
Interventions
Ovarian hyperstimulation, oocyte retrieval and oocyte fertilization will be performed using standard procedures.
In the control arm, one or two fresh embryo(s) will be transferred in the same cycle w
Sponsors
Zorgonderzoek Nederland (ZonMw)
Eligibility
Inclusion criteria
Inclusion criteria: Subfertile couples with female age <43 undergoing IVF (in vitro fertilization) or ICSI (intracytoplasmatic sperm injection).
Exclusion criteria
Exclusion criteria: 1. Couples undergoing a PGD cycle; 2. Couples for which IVF/ICSI is used to prevent the transmission of HIV; 3. Couples undergoing a modified natural cycle; 5. Women with borderline or invasive ovarian cancer; 6. Women with contraindications for IVF/ICSI treatment such as cardiovascular-pulmonary disease, severe diabetes, bleeding disorders, immunodeficiency and morbid obesity; 7. Women with premature ovarian failure; 8. Women with severe psychopathology, severe anxiety and inability to cope with treatment; 9. Not able or willing to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure will be cumulative ongoing pregnancy rate per cycle after twelve months of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will be embryo quality, clinical pregnancy rate, miscarriage rate, live birth rate, time to pregnancy, birth weight and percentage of children with congenital abnormalities. | — |
Contacts
Public ContactFemke Mol
Center for Reproductive Medicine, Amsterdam University Medical Center / University of Amsterdam Room Q3-119; Meibergdreef 9, Amsterdam The Netherlands
Outcome results
None listed