Subfertility and chronic inflammation

Cytokines,vaginal microbiome and subfertility. A pilotstudy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON24178

Enrollment

Registered

2015-07-15

Start date

2015-10-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fertility problems ongewenste kinderloosheid

Interventions

none Research subjects are treated with IUI (IntraUterine Insemination). After informed consent one time bloodsampling + one vaginal swab will be taken for determinations of respectively cytokines an

Eligibility

Inclusion criteria

Inclusion criteria: women with idiopathatic subfertility for a duration of 3 years and more (N=20) lesbian couple and single mothers seeking to fulfill their childwish, with negative histories of cycle irregularity, STD's,, abdominal surgery. (N=20)

Exclusion criteria

Exclusion criteria: 1. free of fever during the past month prior to study entry 2. free of antimicrobial interventions during the past month of study entry 3. positive CAT IgG sampling

Design outcomes

Primary

Measure	Time frame
association between cytokine profile and subfertility association between vaginal microbiome and subfertility are cytokine profiles related to vaginal microbiome patterns?	—

Secondary

Measure	Time frame
Statisitical model to predict which patient variables can be used to quantify the prognosis of subfertility.	—

Contacts

Public ContactJ.P.W. Vermeiden

Hoofd Fertiliteitslaboratorium Nij Barrahûs

j.vermeiden@xs4all.nlTel. 0561610030 Of 0646161592

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)