FDG-PET infection bacteremia metastatic infection Staphylococcus aureus Streptococcus species Enterococcus species endocarditis
Conditions
Interventions
FDG-PET will be performed within 14 days after intiatiation of treatment. The attending physician will be informed of the results of FDG-PET immediately. Special attention will be paid to confirmation
Sponsors
Prof. dr. W.J.G. Oyen
Department of Nuclear Medicine
Radboud University Nijmegen Medical Centre
P.O. Box 9101, 6500 HB Nijmegen
The Netherlands
T: 31 (0)24 3614048
Prof dr. B.J. Kullberg
Department of Internal Medicine
Radboud University Nijmegen Medical Centre
P.O. Box 9101, 6500 HB Nijmegen
The Netherlands
T: 31 (0)24 3614763
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients with blood cultures containing one of the following microorganisms: a. S. aureus; b. Streptococcus spp (excluding S. pneumoniae); c. Enterococcus spp. 2. AND at least one of the following risk factors for metastatic infection: a. Community acquired infection; b. Signs of infection for more than 48 hrs before initiation of appropriate treatment; c. Skin lesions or other symptoms or signs pointing to possible metastatic infection; d. Fever lasting for more than72 hrs after initiation of appropriate treatment; e. Positive blood cultures for more than 48 hrs after initiation of appropriate treatment; 3. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years; 2. Polymicrobial infection; 3. Pregnancy; 4. Critically ill patients initially admitted to the ICU department for more than 14 days; 5. Chemotherapeutically induced neutropenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse rate of infection. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Attributable mortality; 2. Mortality after relapse; 3. Duration of first admission; 4. Duration of antibiotic treatment; 5. Number of diagnostic procedures performed to confirm metastatic foci, duration of admission due to relapse; 6. Associated costs. | — |
Contacts
Public ContactF.J. Vos
Radboud University Nijmegen Medical Centre, Department of Internal Medicine, 463, P.O. Box 9101
Outcome results
None listed