Complex regional pain syndrome type 1 (CRPS-1)
Conditions
Interventions
Upper extremity CRPS-1: percutaneous blockade of Stellate ganglion at C7 with one single injection of bupivacaïne 0,25%
Lower extremity CRPS-1: percutaneous blockade of lumbar sympathetic chain at L3
Sponsors
Department of Anesthesiology, the Academic Hospital Maastricht
Eligibility
Inclusion criteria
Inclusion criteria: Adult (18 years or more) male or female patiënts with CRPS1 as diagnosed by IASP criteria, with a duration of 12 months or less with moderate to severe pain (mean NRS of more than 4 in the previous week as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain) and one extremity involved.
Exclusion criteria
Exclusion criteria: 1. Patiënts of less than 18 years of age; 2. The existence of significant impairment of blood coagulation or the use of oral anticoagulant medication; 3. Patients suffering from diabetic polyneuropathia; 4. Patients who are unlikely to comply with study requirements; 5. Pregnant women; 6. CRPS1 with a duration of more than 12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain relief in the first week after blockade as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following predictors of pain relief after sympathetic blockade will be measured: 1. Pain intensity on a NRS scale of 0 to 10; 2. Subjective and objective skin temperature; 3. Hyper and hypoesthesia; 4. Allodynia; 5. Hyper and hypoalgesia; 6. The presence of dystonia; 7. Tremor and myoclonus. | — |
Contacts
Public ContactJ. Geurts
Academic Hospital Maastricht (AZM), P.O. Box 5800
Outcome results
None listed